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An Interactive Overview of the Mutational
Abbreviations
- AKT = protein kinase B
- ALK = anaplastic lymphoma kinase
- BICC1 = bicaudal-C family RNA-binding protein 1
- cDNA = complementary deoxyribonucleic acid
- CGP = comprehensive genome profiling
- CRC = colorectal cancer
- DAG = diacylglycerol
- DNA = deoxyribonucleic acid
- EML4 = echinoderm microtubule-associated protein-like 4
- ERK = extracellular signal-regulated kinase
- FGF = fibroblast growth factor
- FGFR = fibroblast growth factor receptor
- FISH = fluorescence in situ hybridization
- FRS2α = fibroblast growth factor receptor substrate 2 alpha
- GRB2 = growth factor receptor-bound protein 2
- IHC = Immunohistochemistry
- MEK = mitogen-activated protein kinase kinase
- MDS = myelodysplastic syndromes
- mRNA = messenger ribonucleic acid
- NGS = next-generation sequencing
- NSCLC = non–small cell lung cancer
- PCR = polymerase chain reaction
- PI3K = phosphatidylinositol 3-kinase
- PLCγ = phospholipase C gamma
- RAF = rapidly accelerated fibrosarcoma kinase
- RNA = ribonucleic acid
- RT-PCR = reverse transcriptase polymerase chain reaction
- SOS = son of sevenless
- STAT = signal transducer and activator of transcription
- TACC2 = transforming acidic coiled-coil-containing protein 2
- WT = wild type
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